The Journal of Organic Chemistry

Synthesis of a 16-Membered Cyclic Peptide Model of the BCF Rings of Ristocetin A Using Arene-Ruthenium Chemistry Coupled with Cycloamidation

AJ Pearson, K Lee

文献索引：Pearson, Anthony J.; Lee, Kieseung Journal of Organic Chemistry, 1995 , vol. 60, # 22 p. 7153 - 7160

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被引用次数: 38

摘要

A convergent synthetic approach to the cyclic peptide 4, which is a model for the B/C/F ring system of ristocetin B, is described. A key reaction is the coupling of the phenolic dipeptide 5, constructed from arylglycine subunits, with the chlorophenylalanine-RuCp cationic