Local anesthetics III. Dialkylaminoalkoxyphenylethanol esters

SL Shapiro, H Soloway, HJ Shapiro…

文献索引：Shapiro,S.L. et al. Journal of Pharmaceutical Sciences, 1961 , vol. 50, p. 769 - 771

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被引用次数: 3

摘要

I RI, R? = lower alkyl K1 + RP = lower alkylene Y = ethylene, propylrne, and trimethylene RI = hydrogen and methyl Rq = hydrogen, alkyl, alkoxy, and halogen ... For the reactant alcohols, the amino alcohol, RI,R2N-Y-OH (in excess) was condensed under aIkoxide catalysis (5) with styrene oxide. This reaction, while affording the desired dialkyl- aminoalkoxyphenylethanols (Table I), was clearly not as straightforward as the condemation of secondary amines with ...