Synthesis of Triple Helix Forming Oligonucleotides with a Phenanthroline Moiety into the 3′??3′ Inversion Site of Polarity

…, L Mayol, G Oliviero, A Randazzo…

文献索引：Esposito, Veronica; Galeone, Aldo; Mayol, Luciano; Oliviero, Giorgia; Randazzo, Antonio; Varra, Michela European Journal of Organic Chemistry, 2002 , # 24 p. 4228 - 4233

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被引用次数: 3

摘要

Abstract A protocol for the synthesis of triplex forming oligonucleotides containing a chelating molecule in the 3′-3′ inversion site of polarity is reported. A number of 16-mers have been synthesized and UV spectroscopy employed to evaluate the stability of their triple helix complexes with the pertinent double-strand oligonucleotide targets.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2002)