Tetrahedron

A new enzymatic synthesis of (R)-γ-chloro-β-hydroxybutyronitrile

T Nakamura, T Nagasawa, F Yu, I Watanabe…

文献索引：Nakamura, Tetsuji; Nagasawa, Toru; Yu, Fujio; Watanabe, Ichiro; Yamada, Hideaki Tetrahedron, 1994 , vol. 50, # 41 p. 11821 - 11826

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被引用次数: 36

摘要

A new enzymatic synthesis of (R)-γ-chloro-β-hydroxybutyronitrile from epichlorohydrin or 1, 3-dichloro-2-propanol using halohydrin hydrogen-halide-lyase purified from a recombinant Escherichia coli that carried the enzyme gene of Corynebacterium sp. strain N-1074 was described.