Synthesis of methoxy-substituted phenols by peracid oxidation of the aromatic ring

…, G Occhipinti, C Gambarotti, L Cerasino…

文献索引：Bjorsvik, Hans-Rene; Occhipinti, Giovanni; Gambarotti, Cristian; Cerasino, Leonardo; Jensen, Vidar R. Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7290 - 7296

全文：HTML全文

被引用次数: 19

摘要

A novel benign protocol for the preparation of hydroxy-methoxybenzene derivatives is disclosed. By utilizing this protocol, activated aromatic compounds such as 1, 3-dimethoxy-2- methyl-benzene and 1-(2, 6-dimethoxyphenyl) ethanone are smoothly converted to the corresponding monohydroxylated compound. The reaction can be considered to be a normal aromatic electrophilic substitution reaction, and the regioselectivity for the reaction ...