Synthesis

New simple polymeric supports with hydrazone linkers for solid-phase synthesis of ketones and primary amines

R Lazny, A Nodzewska, K Wolosewicz

文献索引：Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol Synthesis, 2003 , # 18 p. 2858 - 2864

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被引用次数: 12

摘要

Abstract The preparation of new solid supports with hydrazine anchoring groups and their application to solid-phase synthesis of ketones and primary amines are described. The supports were used for immobilization of ketones, 4-tert-butylcyclohexanone, pentan-3-one, acetone, N-methylpiperidone, N-benzylpiperidone, and tropinone in the form of their hydrazones. The polymer-supported hydrazones were subjected to deprotonation/ ...