Structure–activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode

RC Neugebauer, U Uchiechowska…

文献索引：Ohta, Akihiro; Inoue, Akira; Watanabe, Tokuhiro Heterocycles, 1984 , vol. 22, # 10 p. 2317 - 2321

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被引用次数: 132

摘要

... Volume: Page: ... activity has been tied to the pathogenesis of HIV(5) and cancer(6-8) and also neurological diseases.(9, 10) Only a ... screening, and for the first time, anticancer activity in an animal model could be demonstrated using this compound.(22) Using a ...