Journal of Heterocyclic Chemistry

Synthesis of bridgehead nitrogen heterocycles

JP Scovill, JH Burckhalter

文献索引：Scovill, John P.; Burckhalter, Joseph H. Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 23 - 27

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被引用次数: 2

摘要

Abstract Reductive cyclizations of N-[2-(2-pyridyl) ethyl] imides were accomplished by employing a palladium on carbon catalyst in ethanolic acetic acid as the hydrogenation medium. Reduction of the corresponding N-[2-(2-quinolyl) ethyl] imides ceased at the 1, 2, 3, 4-tetrahydroquinolyl stage. Controlled reduction of the tetrahydroquinolyl imides with sodium borohydride gave amido alcohols which afforded bridgehead nitrogen heterocycles upon ...