Enantioselective synthesis of (R)-(−)-baclofen using Fischer-type carbene anions

…, S Maiorana, C Baldoli, L Capella, D Perdicchia

文献索引：Licandro, Emanuela; Maiorana, Stefano; Baldoli, Clara; Capella, Laura; Perdicchia, Dario Tetrahedron Asymmetry, 2000 , vol. 11, # 4 p. 975 - 980

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被引用次数: 42

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The antispastic drug (R)-(−)-baclofen has been synthesized enantioselectively using a diastereoselective Michael addition reaction of the conjugate base of an enantiopure Fischer-type amino carbene to p-chloro-nitrostyrene. ... During the course of our work on new metallocarbenes and their ...