Journal of the Chemical Society C: Organic

Potentially carcinogenic cyclopenta [a] phenanthrenes (1, 2-cyclopentenophenanthrenes). Part II. Derivatives containing further unsaturation in ring D

MM Coombs

文献索引：Coombs,M.M. Journal of the Chemical Society [Section] C: Organic, 1966 , p. 963 - 968

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被引用次数: 3

摘要

Substituted 17-methyl-15H-cyclopenta [a] phenanthrenes have been prepared from the corresponding 15, 16-dihydro-17-ketones by the Grignard reaction, and reduced to the analogues of the Diels hydrocarbon. The 15, 16-dihydro-17-methylene-derivative (unsubstituted) was obtained by the Witting reaction. Elimination from the 17-toluene-p- sulphonyloxy-compound at 170° gave the Δ15–17H-compound (A), but at 100° the Δ16– ...