Tetrahedron: Asymmetry

Stereoselective amination of chiral enolates: Synthesis of chiral key intermediates for β-lactam antibiotics

C Cativiela, MD Díaz-de-Villegas, JA Galvéz

文献索引：Cativiela, Carlos; Diaz-de-Villegas, Maria D.; Galvez, Jose A. Tetrahedron: Asymmetry, 1994 , vol. 5, # 8 p. 1465 - 1468

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被引用次数: 12

摘要

Abstract Stereoselective enolate trapping of lithium (1S, 2R, 4R)-10- dicyclohexylsulfamoylisobornyl-2-cyano-3-phenylpropanoate with O-(diphenylphosphinyl) hydroxylamine followed by appropriate reduction, hydrolysis, and cyclisation processes allows the asymmetric synthesis of (S)-3-amino-3-benzyl-2-azetidinone.