Synthese de cetones aliphatiques encombrees: Action des organolithiens sur les dimethyl-4, 4 oxazolines-2. Addition des organometalliques sur les sels de dimethyl- …
α, α-Disubstituted ketones result from the reaction of organolithium compounds with substituted 4, 4-dimethyl-2-oxazolines, 4, after hydrolysis of the intermediate enamine. Alkylation of the latter also permits the synthesis of α, α, α-trisubstituted ketones. α, α- Disubstituted ketones have been prepared by addition of organometallic reagents to 4, 4- dimethyl-2-oxazolinium salts, 6. The efficiency of this method has been compared to that ...
