Synthesis of Ketones of the Type CH3COCH2R from Acetylacetone and Halides with Ethanolic Potassium Carbonate. An Alkylation—Cleavage Process1

S Boatman, TM Harris, CR Hauser

文献索引：Boatman,S. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 3321 - 3324

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被引用次数: 21

摘要

It is well known that acetylacetone can be alkylated with an alkyl halide by means of a suitable base2 and that the resulting alkyl derivative can be cleaved by an alcoholic base. 3 We have effected such an alkylation-cleavage process to form ketones of type I1 in a single procedure by means of ethanolic potassium carbonate; in certain cases a dialliylation- cleavage process to forin ketones of type IV was also observed (Scheme