A series of forty-six aminooxy derivatives and thirty-six analogs of 7-aminobutyric acid was prepared and tested for inhibition of yaminobutyric acid transaminase and for protection against thiosemicarbazide-induced convulsions. Good in vivo activity in these tests was generally limited to certain a-aminooxyacids or their easily hydrolyzed derivatives, such as esters. None of the compounds studied was superior to aminooxyacetic acid.
![2-[(isopropylideneamino)oxy]-ethanol结构式](https://image.chemsrc.com/caspic/089/83495-51-6.png)
