Journal of heterocyclic chemistry

Some reactions of 1??methyl??(2??phenylethyl)??1, 2, 3, 4??tetrahydropyridines with organic azides. Synthesis of 1??methyl??(2??phenylethyl) piperidylidene??2??sulfonamides

BK Warren, EE Knaus

文献索引：Warren, Brent K.; Knaus, Edward E. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1413 - 1416

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被引用次数: 9

摘要

Abstract The 1, 3-dipolar cycloaddition reaction of 1-methyl-and 1-(2-phenylethyl)-1, 2, 3, 4- tetrahydropyridines 7 with organic azides 8 afforded the respective 1-substituted- piperidylidene-2-sulfon (cyan) amides 9. Nitration of the 1-(2-phenylethyl) analogue 9o yielded the 1-[2-(4-nitrophenyl) ethyl] derivative 9r which on reduction with palladium-on- charcoal and hydrazine gave the 1-[2-(4-aminophenyl) ethyl] analogue 9s.