Synthetic communications

Organic Reactions in Ionic Liquids: Gewald Synthesis of 2??Aminothiophenes Catalyzed by Ethylenediammonium Diacetate

Y Hu, ZC Chen, ZG Le, QG Zheng

文献索引：Hu, Yi; Chen, Zhen-Chu; Le, Zhang-Gao; Zheng, Qin-Guo Synthetic Communications, 2004 , vol. 34, # 20 p. 3801 - 3806

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被引用次数: 44

摘要

Abstract Ionic liquids based on 1??butyl??3??methylimidazolium tetrafluoroborate (BmimBF4) and 1??butyl??3??methylimidazolium hexafluorophosphate (BmimPF6) were used as reusable alternatives to volatile organic solvents (VOCs) for ethylenediammonium diacetate (EDDA) catalyzed Gewald synthesis of 2??aminothiophenes. Significant rate enhancement and improvement of the yield were observed. The ionic liquids containing catalyst EDDA were ...