Synthesis and analgesic activity of some substituted 1-benzofurans and 1-benzothiophenes

…, P Hezký, P Konvička, I Krejčí

文献索引：Radl, Stanislav; Hezky, Petr; Konvicka, Petr; Krejci, Ivan Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 7 p. 1093 - 1108

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被引用次数: 20

摘要

Abstract 2-Benzoyl-and 2-(pyridylcarbonyl)-1-benzofuran-3-amines were prepared from 2- hydroxybenzonitrile and corresponding bromoethanone derivatives. 2-Benzoyl-and 2- (pyridylcarbonyl)-1-benzothiophene-3-amines were prepared analogously from 2- sulfanylbenzonitrile. 2-Benzoyl-1-benzofuran-3-amine treated with acetic anhydride or ethyl chloroformate provided the corresponding N-acetyl or N-ethoxycarbonyl derivatives. ...