First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects

…, A Vessières, P Pigeon, G Leclercq, I Laios

文献索引：Jaouen; Top; Vessieres; Pigeon; Leclercq; Laios Chemical Communications, 2001 , # 4 p. 383 - 384

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被引用次数: 48

摘要

A route to the organometallic complex 8 is described, along with a study of its antiproliferative effects on breast cancer cell lines; in the examples studied, 8 behaves in a very similar manner to tamoxifen, suggesting new possibilities for applications in organometallic chemistry.