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Journal of heterocyclic chemistry

Synthesis of new 1, 2??dihydrophthalazines

G Lukács, G Simig

文献索引:Lukacs, Gyula; Simig, Gyula Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 5 p. 989 - 996

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被引用次数: 7

摘要

Abstract New 6-chloro-and 6, 7-dichloro-4-(4-aminophenyl)-2-(N-alkylcarbamoyl)-1, 2- dihydrophthalazines (12, 18) were synthesized starting from 6-chloro-and 6, 7-dichloro-4-(4- nitrophenyl) phthalazine (8). Routes to 1-unsubstituted (12) and 1-methyl (18) derivatives are different. Key intermediates 8 were prepared from 4-chloro-and 3, 4-dichlorotoluene via ortho-formylbenzophenone derivatives 7.