Potential Bile Acid Metabolites; 12. Synthesis of Stereoisomeric 3, 7, 12-Trihydroxy-5α-cholanic Acids and Related Compounds

…, T Shinohara, T Momose, T Tamura, T Matsumoto…

文献索引：Iida, Takashi; Shinohara, Toshiyuki; Momose, Toshiaki; Tamura, Toshitake; Matsumoto, Taro; et al. Synthesis, 1986 ,  # 12  p. 998 - 1004

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被引用次数: 8

摘要

The complete set of the eigit 'tlieoreiic-ally possible stereoisomeric 3,',-', I_Z-trihydroxy-Sat- cholanic acids. five of which are now, were prepared hy reduction of the four possible 3, 7- dihydroxy-t2-oxo-Sat-esters. These esters. obtained by use of the inverting reagents, potassium supermtidol8-crown--6 ether aiidlor diinethylformalnidc. by stereoseleetive reduction with sodiuin horohydride-palladium dichloride or r-hutylamine-borane complex ...