4-Aryl/cycloalkyl-5-phenyloxazole derivatives as selective COX-2 inhibitors

H Hashimoto, K Maeda, K Ozawa, J Haruta…

文献索引：Hashimoto, Hiromasa; Maeda, Kimiya; Ozawa, Koichi; Haruta, Jun-Ichi; Wakitani, Korekiyo Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 1 p. 65 - 68

全文：HTML全文

被引用次数: 15

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of 4-aryl/cycloalkyl-5-phenyloxazole derivatives was synthesized and evaluated for their ability to inhibit cyclooxygenase-2 (COX-2) and cyclooxygenase-1 (COX-1). These compounds were found to be potent and selective COX-2 inhibitors. ... A series of 4-aryl/cycloalkyl-5- ...