Synthetic Communications

6-Endo Heck Cyclization of 3-(2-Iodophenoxy) methylbenzofurans: A Useful Approach to Pterocarpenes

KJ Fowler, JL Ellis, GW Morrow

文献索引：Fowler, Katherine J.; Ellis, Jillian L.; Morrow, Gary W. Synthetic Communications, 2013 , vol. 43, # 12 p. 1676 - 1682

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被引用次数: 6

摘要

Mitsunobu coupling of 3-hydroxymethylbenzofurans with o-iodophenols affords 3-(2-iodophenoxy)methylbenzofurans which under go a useful 6-endo Heck cyclization under Jeffery conditions to afford pterocarpene-type heterocycles. The unsubstituted parent pterocarpene thus prepared was readily converted to coumestan via subsequent PCC oxidation. ... Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic ...