European Journal of Organic Chemistry

Selective Synthesis of Isoquinolin??3??one Derivatives Combining Pd??Catalysed Aromatic Alkylation/Vinylation with Addition Reactions: The Beneficial Effect of Water

R Ferraccioli, A Forni

文献索引：Ferraccioli, Raffaella; Forni, Alessandra European Journal of Organic Chemistry, 2009 , # 19 p. 3161 - 3166

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被引用次数: 9

摘要

Abstract The three-component, palladium/norbornene-catalysed reaction of 1, haloamides 2 and properly substituted olefins 3 performed in DMF/water at 80 C selectively gave 5 and 6 through three-and four-bond-forming reactions, respectively. The presence of water was crucial to obtain products in fair to good yields.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)