前往化源商城

Enantio??and Diastereoselective Catalytic Mannich??Type Reaction of a Glycine Schiff Base Using a Chiral Two??Center Phase??Transfer Catalyst

A Okada, T Shibuguchi, T Ohshima…

文献索引:Okada, Akihiro; Shibuguchi, Tomoyuki; Ohshima, Takashi; Masu, Hyuma; Yamaguchi, Kentaro; Shibasaki, Masakatsu Angewandte Chemie - International Edition, 2005 , vol. 44, # 29 p. 4564 - 4567

全文:HTML全文

被引用次数: 121

摘要

Akihiro Okada, Tomoyuki Shibuguchi, Takashi Ohshima,* Hyuma Masu, Kentaro Yamaguchi, and Masakatsu Shibasaki* α, β-Diamino acids are key structural components in molecules such as peptides and β-lactam antibiotics and in medicinally relevant compounds;[1, 2] for example, 2, 3-diamino-3-phenylpropanoic acid is used as an advanced alternative to the side chain of taxol to improve its water solubility.[3]