1, 2-Diamino-4, 5-methylenedioxybenzene as a highly sensitive fluorogenic reagent for. ALPHA.-keto acids.

…, S Hara, M Yamaguchi, Y Takemori, Y Ohkura

文献索引：Nakamura, Masaru; Hara, Shuuji; Yamaguchi, Masatoshi; Takemori, Yasuyo; Ohkura, Yosuke Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 2 p. 687 - 692

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被引用次数: 55

摘要

The reactivity of pyruvic acid with 1, 2-diaminobenzenes was investigated as part of a survey of fluorogenic reagents for α-keto acids of biological importance. Of eight 1, 2- diaminobenzenes tested, 1, 2-diamino-4, 5-methylenedioxybenzene was found to be the best reagent in terms of sensitivity and reactivity. The reagent reacts with α-keto acids in an acidic solution to produce the corresponding fluorescent derivatives, which fluorescent ...