Tetrahedron letters

An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764

T Yamanaka, M Ohkubo, F Takahashi, M Kato

文献索引：Yamanaka, Toshio; Ohkubo, Mitsuru; Takahashi, Fumie; Kato, Masayuki Tetrahedron Letters, 2004 , vol. 45, # 13 p. 2843 - 2845

全文：HTML全文

被引用次数: 15

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764 was achieved. The key intermediate, an optically active ethynyl β-amino ester, was synthesized efficiently by utilizing a lipase catalyzed kinetic resolution step. ... An efficient synthesis of the orally-active ...