Synthesis

Rhodium-catalyzed Heck-type coupling of boronic acids with activated alkenes in an aqueous emulsion

M Lautens, J Mancuso, H Grover

文献索引：Lautens, Mark; Mancuso, John; Grover, Harpreet Synthesis, 2004 , # 12 p. 2006 - 2014

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被引用次数: 15

摘要

Abstract Intermolecular couplings between arylboronic acids and activated alkenes catalyzed by a water-soluble tert-butyl amphos-rhodium complex were found to progress at room temperature and generated Heck-type products with high yields and excellent selectivity. Substitution on the alkene component encouraged the formation of products arising from a conjugate addition-protonation process. In the case of Heck product ...