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Development of an Efficient and Stereoselective Manufacturing Route to Idoxifene

KW Ace, MA Armitage, RK Bellingham…

文献索引:Organic Process Research and Development, , vol. 5, # 5 p. 479 - 490

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被引用次数: 9

摘要

... Organic Process Research & Development. ... a concerted elimination of a diastereomerically enriched substrate 11 could be performed (Scheme 4). The research pursued a ... yield of ketone 13 (48%) that was isolable without chromatography (Scheme 6). This procedure was used ...