Three new substrates with an aryl amine moiety attached to quinoxalines, triazoles and tetrazoles either via C or N have been used for the Pictet–Spengler reaction. The substrates have been designed by applying the concept of 'aryl amine attached to a deactivated heteroaromatic ring'in a manner to facilitate endo cyclization. This is in contrast to the substrates used traditionally and reported earlier by us that are based on either aliphatic ...
