New practical synthesis of 5??formylindole

J Fetter, F Bertha, L Poszávácz…

文献索引：Fetter, Jozsef; Bertha, Ferenc; Poszavacz, Laszlo; Simig, Gyula Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 1 p. 137 - 139

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被引用次数: 15

摘要

Functionalised indoles are of interest in pharmaceutical industry as the indole ring is a structural element of many biologically active compounds. In the course of making plans for the elaboration of a new manufacturing synthesis of the antimigraine drug naratriptan (1, Figure 1) [1], we came to the conclusion that 5-formylindole (2) could serve as the starting compound. ... The traditional approach for the synthesis of 5-formylin- dole is based on the transformation of 5- ...