Papain catalysed esterification of N-protected amino acids

ST Chen, KT Wang

文献索引：Chen, Shui-Tein; Wang, Kung Tsung Journal of the Chemical Society, Chemical Communications, 1988 , # 4 p. 327 - 328

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被引用次数: 16

摘要

The esterification of amino acids with alcohols is an important reaction. Although there are many chemical methods,' only a few simple processes are effective under mild conditions.2 Recently the mono-esterification of N-protected diacids using chloroformate activation was reported3 but the products contained about 10-34% of positional isomers and separa- tion was difficult. We describe here a new enzymatic procedure for preparative esterification of N-protected ...