前往化源商城

The Journal of Organic Chemistry

The Mechanism of Action of Bisalkylating Agents in Cancer Chemotherapy. II. The Reaction of Myleran with Mercaptans1

WE PARHAM, JM WILBUR Jr

文献索引:Parham,W.E.; Wilbur,J.M. Journal of Organic Chemistry, 1961 , vol. 26, p. 1569 - 1572

全文:HTML全文

被引用次数: 10

摘要

It is unreasonable to assume that XVII is formed by either an SN-1 or SN-2 reaction of mercaptide at CZ (in XV) in view of the results previously obtained with butyl and methyl mercaptan, and incompatible with the previous observation that the reaction of myleran with the sodium salt of cysteine ethyl ester affords VI.