Bleomycin: synthesis and structural verification of the tripeptide S and tetrapeptide S moieties

MD Levin, K Subrahamanian, H Katz…

文献索引：Levin; Subrahamanian; Katz; et al. Journal of the American Chemical Society, 1980 , vol. 102, # 4 p. 1452 - 1453

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被引用次数: 10

摘要

The antitumor antibiotic bleomycin has attracted considerable interest because of its activity against certain human malignancies and the prospect that new bleomycin analogues may find even greater utility in the clinic.'S2 A structure was first proposed for bleomycin in 19723 and has recently been revised to that shown (1, bleomycin A2). 4 Additionally, the