Organic letters

New methodology toward α, β-unsaturated carboxylic acids from saturated acids

Q Li, GP Tochtrop

文献索引：Li, Qingjiang; Tochtrop, Gregory P. Organic Letters, 2014 , vol. 16, # 5 p. 1382 - 1385

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被引用次数: 2

摘要

A carefully designed three-step unsaturation of carboxylic acids is described. Briefly, carboxylic acids were converted to the trifluoromethyl ketone. Subsequent treatment with selenium dioxide followed by hydrolysis afforded α, β-unsaturated carboxylic acids. The