Synthesis and biological evaluation of novel piperidin-4-ol derivatives

Z Weng, W Wei, X Dong, Y Hu, S Huang, T Liu…

文献索引：Weng, Zhiyong; Wei, Wei; Dong, Xiaowu; Hu, Yongzhou; Huang, Shufang; Liu, Tao; Xie, Xin Monatshefte fur Chemie, 2012 , vol. 143, # 2 p. 303 - 308

全文：HTML全文

被引用次数: 1

摘要

Abstract A series of novel piperidin-4-ol derivatives were designed, synthesized, and evaluated for potential treatment of HIV. The compounds were obtained via an efficient synthetic route in excellent yields and have been characterized by 1 H NMR, 13 C NMR, MS, and elemental analysis. The CCR5 antagonistic activities of the compounds have also been evaluated. Graphical abstract