Enabling Nucleophilic Substitution Reactions of Activated Alkyl Fluorides through Hydrogen Bonding

PA Champagne, J Pomarole, ME Thérien…

文献索引：Organic Letters, , vol. 15, # 9 p. 2210 - 2213

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被引用次数: 26

摘要

... Volume: Page: Digital Object Identifier (DOI). ... Organic Letters. ... Conversions of 1a to 2 were estimated by 1 H NMR of the crude mixture.(16). To circumvent the solubility issue encountered with water, mixtures of organic solvent/water were next explored. ...