Simple and convenient methods for synthesis, resolution and application of aminonaphthols

M Periasamy, S Anwar, MN Reddy

文献索引：Periasamy, Mariappan; Anwar, Shaik; Reddy, Meda Narsi Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009 , vol. 48, # 9 p. 1261 - 1273

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被引用次数: 7

摘要

Abstract: Racemic aminonaphthols are obtained in 70-95% yield by simple and straightforward condensation of benzaldehyde, 2-naphthol and 1 or 2 amines in ethanol solvent under refluxing conditions. The racemic aminonaphthols 1-(α-aminobenzyl)-2- naphthol and 1-(α-pyrrolidinylbenzyl)-2-naphthol have been resolved using l-(+)-tartaric acid. The racemic 1-(α-N-butylaminobenzyl)-2-naphthol and 1-(α-piperidylbenzyl)-2- ...