Journal of fluorine chemistry

Direct fluorination of aryl ketone hydrazones

TB Patrick, PA Flory

文献索引：Patrick,T.B.; Flory,P.A. Journal of Fluorine Chemistry, 1984 , vol. 25, p. 157

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被引用次数: 13

摘要

Abstract The hydrazones of benzophenone, acetophenone, and deoxybenzoin react with dilute fluorine to produce intermediate diazo compounds which react further with the fluorine or nascent hydrogen fluoride to give geminal difluoro or monofluoro derivatives respectively of the starting hydrazones. The fluorination procedure has been applied to two biological systems, 1 and 2, with their conversion to monofluoro compounds 3 and 4.