前往化源商城

Novel hexadentate and pentadentate chelators for 64 Cu-based targeted PET imaging

I Sin, CS Kang, N Bandara, X Sun, Y Zhong…

文献索引:Sin, Inseok; Kang, Chi Soo; Bandara, Nilantha; Sun, Xiang; Zhong, Yongliang; Rogers, Buck E.; Chong, Hyun-Soon Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 8 p. 2553 - 2562

全文:HTML全文

被引用次数: 4

摘要

Abstract A series of new hexadentate and pentadentate chelators were designed and synthesized as chelators of 64 Cu. The new pentadentate and hexadentate chelators contain different types of donor groups and are expected to form neutral complexes with Cu (II). The new chelators were evaluated for complex kinetics and stability with 64 Cu. The new chelators instantly bound to 64 Cu with high labeling efficiency and maximum specific ...