Asymmetric total syntheses of (-)-and (+)-strychnine and the Wieland-Gumlich aldehyde

…, LE Overman, G Pairaudeau

文献索引：Knight, Steven D.; Overman, Larry E.; Pairaudeau, Garry Journal of the American Chemical Society, 1995 , vol. 117, # 21 p. 5776 - 5788

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被引用次数: 124

摘要

Abstract: The fist asymmetric total syntheses of (-)-strychnine, ent-strychnine, and the Wieland-Gumlich aldehyde are described with full experimental details. The total synthesis of (-)-strychnine was realized in 24 steps and 3% overall yield from (1R, 4S)-(f)-4-hydroxy- ...