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TOPP: A Novel Nitroxide??Labeled Amino Acid for EPR Distance Measurements

…, G Sicoli, TY Baranova, M Bennati…

文献索引:Stoller, Sven; Sicoli, Giuseppe; Baranova, Tatiana Y.; Bennati, Marina; Diederichsen, Ulf Angewandte Chemie - International Edition, 2011 , vol. 50, # 41 p. 9743 - 9746

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被引用次数: 17

摘要

Electron paramagnetic resonance (EPR) spectroscopy is a well-established technique for the structural study of biomolecules.[1] In particular, over the past decade distance measurements between methanethiosulfonate spin labels (MTSSL) attached to cysteine residues of proteins or peptides have been successfully established.[2] Recently, not only the distance but also the relative orientation of essential amino acid radicals rigidly ...