Synthesis of 1, 3, 4??Trisubstituted Isoquinolines by Iodine??Mediated Electrophilic Cyclization of 2??Alkynyl Benzyl Azides

D Fischer, H Tomeba, NK Pahadi…

文献索引：Fischer, Dirk; Tomeba, Hisamitsu; Pahadi, Nirmal K.; Patil, Nitin T.; Yamamoto, Yoshinori Angewandte Chemie - International Edition, 2007 , vol. 46, # 25 p. 4764 - 4766

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被引用次数: 136

摘要

Isoquinolines are an important class of alkaloids commonly found in natural products.[1] Their biological activities have resulted in them often being used as building blocks in pharmaceutical compounds,[2] as chiral ligands for transitionmetal catalysts,[3] and their iridium complexes in organic lightemitting diodes (OLEDs).[4]