Ruthenium-catalyzed amidation of nitriles with amines. A novel, facile route to amides and polyamides

S Murahashi, T Naota, E Saito

文献索引：Murahashi, Shun-Ichi; Naota, Takeshi; Saito, Eiichiro Journal of the American Chemical Society, 1986 , vol. 108, # 24 p. 7846 - 7847

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被引用次数: 135

摘要

In the field of amide synthesis, a problem of continuing interest is the development of a general method for the conversion of amines to amides under neutral c0nditions. l Toward this end we have devised a new type of highly efficient method, which is applicable for synthesis of various amides and polyamides. Ruthenium-catalyzed condensation of nitriles with amines in the presence of 2 equiv of water provides the corresponding amides along ...