Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds

DI Perez, V Palomo, C Pérez, C Gil…

文献索引：Kallmayer, Hans-Joerg; Wagner, Eugen Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 4 p. 315 - 323

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被引用次数: 39

摘要

... Volume: Page: ... To this end, we have analyzed by HPLC–MS the reaction of compound 3 or 4 with 2-mercaptoethanol at room temperature (Table 3). The reaction afforded 11% and 20% of the S-alkylated product for 3 and 4, respectively, in ...