Three siderophores from one bacterial enzymatic assembly line

WM Wuest, ES Sattely, CT Walsh

文献索引：Wuest, William M.; Sattely, Elizabeth S.; Walsh, Christopher T. Journal of the American Chemical Society, 2009 , vol. 131, p. 5056 - 5057

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被引用次数: 33

摘要

Siderophores play a vital role in the survival of bacteria, as they facilitate the transport of iron in low-concentration environments. Nature employs a variety of coordinating functional groups in siderophore scaffolds as a way of creating structural diversity. We have successfully shown that the pseudomonine synthetase can produce three distinct siderophore natural products and five siderophore-like compounds. The in vitro enzymatic ...