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Organic letters

Three-component strategy toward 5-membered heterocycles from isocyanide dibromides.

LE Kaim, L Grimaud, P Patil

文献索引:Kaim, Laurent El; Grimaud, Laurence; Patil, Pravin Organic Letters, 2011 , vol. 13, # 5 p. 1261 - 1263

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被引用次数: 35

摘要

A three-component strategy starting from isocyanides allows a straightforward synthesis of five-membered ring heterocycles. New cascades were developed involving the addition of a nitrogenated nucleophile an azide or a tetrazole on isocyanide dibromides, an electrocyclization, and a Suzuki coupling, which afford new accesses to tetrazole and triazole scaffolds.