Tyrphostins IV—highly potent inhibitors of EGF receptor kinase. Structure-activity relationship study of 4-anilidoquinazolines

…, H App, G McMahon, P Hirth, I Chen, A Levitzki

文献索引：Gazit, Aviv; Chen, Jeffrey; Harald, App; McMahon, Gerald; Hirth, Peter; Chen, Irit; Levitzki, Alexander Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 8 p. 1203 - 1207

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被引用次数: 80

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Potent 4-anilido-substituted quinazolines which potently inhibit epidermal growth factor receptor (EGFR) kinase were prepared. Structure-activity relationship studies reveal high sensitivity to substitution at the aniline ring. ... Potent 4-anilido substituted quinazolines which potently ...