Environmentally friendly and efficient process for the preparation of β-hydroxyl ketones

GW Wang, Z Zhang, YW Dong

文献索引：Wang, Guan-Wu; Zhang, Ze; Dong, Ya-Wei Organic Process Research and Development, 2004 , vol. 8, # 1 p. 18 - 21

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被引用次数: 31

摘要

An environmentally benign and efficient process for the preparation of β-hydroxyl ketones was developed by the practical cross-aldol reactions of 2-acetylpyridine, acetophenone, and cyclohexanone with 4-nitro-, 3-nitro-, and 2-nitrobenzaldehydes in water catalyzed by Na2CO3 in very high yields.