Organic & biomolecular chemistry

Isocyanate acting as a carbonyl precursor: pyridyl group-assisted formation of 4 H-pyrido [1, 2-a] pyrimidin-4-ones from ketimines and isocyanates

Y Kuninobu, S Nishimura, K Takai

文献索引：Kuninobu, Yoichiro; Nishimura, Shuhei; Takai, Kazuhiko Organic and Biomolecular Chemistry, 2006 , vol. 4, # 2 p. 203 - 205

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被引用次数: 4

摘要

By the reactions of ketimines bearing a pyridyl or a picolyl group on a nitrogen atom of the imine moiety with tosylisocyanate, 4H-pyrido [1, 2-a] pyrimidin-4-one derivatives could be obtained in quantitative yields. In these reactions, tosylisocyanate acts as a carbonyl precursor. The pyridyl or picolyl group is a key functional group because it is not only the constituent structure of the 4H-pyrido [1, 2-a] pyrimidin-4-one framework but also the ...