Abstract Ten 1-substituted arylaminopropyl silamnes (1-X) were synthesized by the reaction of aromatic amines with chloropropyl silatrane and aryl chloride with aminopropyl silatrane respectively. Their structures were identified by elemental analysis. IR, 1HNMR, and MS measurement. An antimicrobial test was done and the result showed that some of them had obvious antibacterial activity.